A lot of the answers seem to be missing the bigger picture.
The objective of science is to extend our understanding of the nature of reality. And to that end we try to weave our observations of reality into a narrative that explains them. What we thus end up with is some sort of toy model or simulation of a (usually) simplified universe. Which has the neat advantage that if we can describe the universe with such a hypothesis, this also allows us to make predictions for how it should behave in unexplored cases if the theory were to be true. Which we can then test.
That being said we almost certainly know that the theory is wrong, because usually it's a massive simplification and based on observations that already came with a margin of error, rather than being precise.
And so the scientific process is a continuous loop of observing, explaining and testing. Where each test is the opportunity to either extend the model to more applications or to have it break and find new properties of the universe that you haven't yet accounted for.
So distrusting the theory is the default and you're almost bound to be correct with that. So BOB IS NOT FLOUTING SCIENCE when he argues to stay open minded. If you're engaged in pure science that is precisely what you ought to do. Never trust the theory, always trying to poke holes in it even if it is all to human to like your own ideas if they are beautiful, elegant, powerful, ...
The problem is: Not all science is pure. As soon as you enter the domain of "science adjacent"-disciplines idk you either drop the uncertainty or you drop reality. Like idk math and logic often times drop reality and get lost in their own models, where they accept a few axioms and then build an entire universe upon the assertions "Assuming XYZ is true" (regardless of the question whether XYZ is ACTUALLY true).
While on the other hand the more applied sciences like idk medicine, engineering, etc, are usually not interested in the purity of models explaining how the world works and much more interested in whether they are good enough approximations so that they "reliably" work in reality. So the explanation might as well be bullshit... as long as it works...
Which brings us to the crucial question that is likely hiding behind yourquestion, namely: "What should we do with scientific theories".
And to the apparent surprise of many people that is not a scientific question but a political one.
Science is only interested in broadening the understanding of the universe and it likely will remain a never ending work in progress, so it cannot provide and doesn't claim to provide eternal truths.
So following the advice of a scientific theory is a gamble upon a(n educated) guess. And ultimately gambling is a decision (or if it involves more than 1 person a collective decision aka political). So science might tell you it's likely a 90:10 coin flip, but whether you test your luck and go for the 10% probability or whether you go for the 90% is a decision that you need to make.
For example if your 90% option is certain death, you might speculate on whatever the 10% option is. While in a different scenario you'd plan with the more likely outcome. All with the asterisk that even the 90:10 probability is a guess.
Though "science" as a whole usually is the collective of all the data and provides you with models trying to explain the data, so you have both some empirical hints as to what is to be expected and you've models that allow you to plan for certain scenarios (under the assumption that these models hold water), which is usually much better than blind guesses or basing your decision making on way fewer data and more unreasonable explanations.
But the outcome of the experiment is decided by reality not by science and it's science that needs to adapt not reality.
So it's not unscientific to be skeptical, on the contrary. Though usually science expects you to engage with the data or to contribute your own. The problem being that pure skepticism and epistemic nihilism are pretty unproductive. Like if you reject the very ability to acquire any knowledge and reject science for being likely incorrect than you end up with a total mist and no direction and poking in that mist is usually way more likely to be incorrect then to rely on all the observations (and ideas how to put these pieces of information together) that we've acquired so far.
So at some point you're likely forced to make a decision an usually an educated guess is still better than a blind guess.
Also last thing worth noting. The reliability of science is also to some extend a matter of time. Like Alice is one person making experiments on a novel subject, so chances are she's not seeing the whole picture but just a fragment of it. So with time more people might find her work interesting and research in that direction revealing more parts of the picture which might extend Alice's work or put it into a different context. Maybe it was all just an outlier, maybe it was a textbook example of something, aso. So the reliability often relies on the data that is being gathered so with respect to novel findings there's usually a lot of hype, but usually the actual scientists try to moderate and argue what it could be not what it is, because it's still very likely that they are "wrong" or perhaps it's better expressed as incomplete.