There is usually the notion the we don't require certainty for knowledge. This usually comes through an assessment of probabilities. This is entailed in induction(which are probabilistic), including inference to the best explanation(the most likely explanation).
But to me this would entail a closed-off, certain base. To say, for example, 1/2 or 1/50, entails the 2 or the 50 to be fixed and certain. Even ranges where it is not fixed but certain and known requires this sort of "containment" of the variables. But how can that be justified? All of this, including the framing seems wildly subjective.
Let's say that every day during 10 years the mailman comes around the corner. We can make an inference that the likelihood that the mailman doesn't come this day is 1/3650 or something of that sort. But this assumes the framing is closed, that the proper, objective "measurement" for inference is the days. Maybe, the mailman didn't come because he got sick, so beyond the 1/3650, we would need to include the likelihood of him having a "can't go to work" sick day. Maybe he was battling terminal cancer, and so the likelihood of him dying would have been far greater than the 1/3,650.
This assumes that our everyday understanding of reality and hence our framing of its local conditions for our analysis can be used to determine things. In short, it bakes in a determination upon which the analysis is built. But how can that determination, which ought to be objective, be determined as such objectively and contained? What if frogs start raining, atoms decompose, what if an unknown cosmic anomaly destroys our planet or our Universe? Our model of reality is contained within as a subset within the limits of our imagination, and the possibilities of reality could far outstrip our imagination, including the possibilities within reality that destroy our determination?