Source:: Hume discusses the problem in book III, part I, section I of his book, A Treatise of Human Nature (1739):
... But as authors do not commonly use this precaution, I shall presume to recommend it to the readers; and am persuaded, that this small attention would subvert all the vulgar systems of morality, and let us see, that the distinction of vice and virtue is not founded merely on the relations of objects, nor is perceived by reason.
Am I right that this small attention means the problem of leaping from [is and is not] to [ought and ought not]? Even if so, how does this subvert all the vulgar systems of morality?