Creative destruction is mentioned in The Will to Power, as active nihilism. This can be introduced with some contextual preamble from Heidegger.
Heidegger, Off the Beaten Track (Brief quotes from pages 158, 162, 166 & 167)
In keeping with the essential involvement of metaphysics (an
involvement that metaphysics itself demands and seeks anew time and
again) with the sciences, themselves the offspring of metaphysics,
preparatory thinking must also move now and then in the area of the
sciences because in many different shapes they are claiming still to
predetermine the fundamental form of knowledge and the knowable,
either knowingly or through the nature of their validity and
Since Plato, or more accurately, since the late Greek and the
Christian interpretations of the Platonic philosophy, this realm of
the supersensory has been considered the true and actually real world.
In contrast to it, the sensory world is only the unreal this-worldly
world, the changeable and therefore the merely apparent world. ...
Metaphysics, which for Nietzsche is Western philosophy understood as
Platonism, is at an end. Nietzsche understands his own philosophy as
the countermovement against metaphysics, i.e., for him, against
In a note from 1887, Nietzsche poses the question (The Will to
Power, aphorism no. 2 ): "What does nihilism mean?" He gives the
answer: "That the highest values devalue themselves." ...
i.e. the Platonic ideal of rationalism dismantles Platonism itself.
By nihilism, Nietzsche understands the devaluation of the hitherto
highest values. Yet at the same time Nietzsche finds himself
affirming nihilism in the sense of a "revaluation of the highest
values." The name "nihilism" is therefore ambiguous; seen in relation
to its extremes, it always has two meanings from the start, in that it
designates the pure devaluation of the former highest values, but at
the same time it also means the absolute countermovement to
Nietzsche, The Will to Power, Aphorism 23
Nihilism, a normal condition. ...
It reaches its maximum of relative strength, as a powerful
destructive force, in the form of active Nihilism.
As for art . . . Aphorism 449.
According to Aristotle, Philosophy is the art of discovering truth. On
the other hand, the Epicurians, who availed themselves of Aristotle's
sensual theory of knowledge, retorted in ironical opposition to the
search for truth: "Philosophy is the art of Life."