There is a long tradition trying to approach knowledge as a true and justified belief (The Tripartite Analysis of Knowledge . Recently, Gettier(1963) just showed that we need more than those 3 conditions, and if we follow Zagzebski (1994), it seems we can always deduce some counterexamples to one or another version of the tripartite analysis of knowledge. A different approach could be:
S knows that p, if and only if, S does NOT ignore p
This way, we could just look for an adequate theory of ignorance.