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Is it reasonable to arrive at a conclusion based on lack of evidence to the contrary?

Short Answer No, as a general rule, it is not appropriate to accept a view solely due to lack of contrary evidence. This is a known fallacy, and it is called an argument from ignorance. A Bit Longer ...
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Is it reasonable to arrive at a conclusion based on lack of evidence to the contrary?

Depends on what how you define "reasonable", upon whether you'd expect to find evidence and on it being a true binary. Like first of all what do you mean by reasonable. Do you want the truth ...
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