Welcome to Plato's Cave. 2500 years later and we're none the wiser. :)
If I observe my mother, is that proof of the existence of my mother?
Technically and strictly, this is only proof that whatever it is that is doing the observing believes that it has observed your mother; nothing more or less. From this you can write a 10.000 word pamphlet about what all the words mean. It really depends on your basic beliefs about how the world and yourself works. Nothing of that is "truly known" (but most philosophers or neuroscientists probably have a strong opinion).
A Bayesian would argue that there is no black & white, and every proposition like P1: "I see my mother", P2: "my mother exists" and even P§: "P1 -> P2" has a probability associated with it, but none of them have the probability 0 or 1. So in their worldview, the argument would probably be that the probabilities for all three propositions are pretty high, bordering 1 very closely (but never absolutely).
If I observe an apple on top of a table, is that proof of the existence of that apple and that table?
The same argument.
Someone might claim that they have observed God. Is that proof of the existence of the God they claim to have observed?
Never. This is completely different. In the previous two examples, you did not mention that you would like to convince someone else than yourself from any of the propositions. This new example has P1: "Someone claims they observed God.", P2: "God exists" and P3: "P1 -> P2".
For a Bayesian, the probabilities would be "pretty high" for P1 - there are plenty of precedents of people claiming they observed God in some form or fashion. P2 is completely "free floating" depending on the belief system of the Bayesian at hand. But P3: "P1 -> P2" must be close to zero.
The latter is the simple proposition that solely because someone said something, this must be true. That is a very weak argument. Everybody can say anything whatsoever. Humans are perfectly capable of deceiving, fantasizing, inventing stuff, misinterpreting their observations or plain old lying. Extraordinary claims require extraordinary proofs, so someone simply saying something has no or very little effect on the probabilities of anything.
The more analogous case to your previous two examples would be: "If I observe God, is that proof of the existence of God (to me)." You can do the analysis like before for yourself - the probabilities of this statement (for you) basically reflect whether you already believe or not, or where you are on the spectrum.
More generally, can the observation of anything prove the existence of anything, and if so, under what circumstances?
The term "prove" is difficult here. What does it mean? Experience shows that nothing at all is a "proof" of anything, regarding reality; no matter how well you think you know things, you always have to be open to amending your beliefs. The whole scientific method is built on the concept that we do not even pretend to prove anything at all - we only make theories with a recipe for disproving them; and then work with those theories until disproven. But no scientist ever assumes that any of the theories is fundamentally, objectively "true" forever.
In other areas (philosophy, religion etc.), the concept of "proof" does not even exist, at least not in a meaning one would commonly think it has. If you think of mathematical proofs, they most definitely do not stem from simple observations; they come from creating an abstract, purely self-contained building based on arbitrary axioms and pretty few, strict, logical operations built on top on the axioms. And mathematicians are not even agreeing on which axioms and operations are "correct".